Search on: DNA GLYCOSYLASES 
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Descriptor English:   DNA Glycosylases 
Descriptor Spanish:   ADN Glicosilasas 
Descriptor Portuguese:   DNA Glicosilases 
Synonyms English:   DNA N-glycosidase  
Tree Number:   D08.811.074.249
D08.811.277.450.430.099
Definition English:   A family of DNA repair enzymes that recognize damaged nucleotide bases and remove them by hydrolyzing the N-glycosidic bond that attaches them to the sugar backbone of the DNA molecule. The process called BASE EXCISION REPAIR can be completed by a DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE which excises the remaining RIBOSE sugar from the DNA. 
History Note English:   2004; use DNA GLYCOSIDASES (NM) 1980-2003 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   38126 
Unique Identifier:   D045647 

Occurrence in VHL:
 

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